Iron-related modification of bacterial transfer RNA

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Iron-related modification of bacterial transfer RNA.

Transfer RNAs isolated from E. coli grown in media where ferric iron is not freely available show well characterized chromatographic changes due to the absence of the methylthio moiety of ms2i6A. The altered tRNA molecules include tRNA trp tRNA tyr, tRNA phe and two minor tRNA ser species. It has been suggested that methylthiolation of tRNA affects its function in regulation. We now show iron-r...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 1981

ISSN: 0305-1048,1362-4962

DOI: 10.1093/nar/9.11.2629